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Insulin Receptor Substrate-1 Deficiency Drives a Proinflammatory Phenotype in KRAS Mutant Lung Adenocarcinoma

T cells regulate the intestinal response to nutrient sensing

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Current treatment strategies aim to improve insulin resistance via weight loss and exercise, improve insulin sensitivity by the use of insulin-sensitizing agents (for example, pioglitazone) and reduce oxidative stress by the use of antioxidants, such as vitamin E