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In a new Journal of American Chemical Society study, Krishna Kumar, Martin Beinborn, and co-workers from Tufts University unveil the first unimolecular tetra-agonistspeptides that activate GLP-1R, GIPR, GcgR, and Y2R all at once

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The bigger message is that these agents are pushing us toward a more integrated cardiometabolic model of care, in which obesity, heart failure, kidney disease, liver disease, and vascular risk are treated as connected biology rather than asseparate silos.

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