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Early findings around GLP-1s and addiction preclinical research suggest: Reduced drug-seeking behaviors in animal models involving opioids, nicotine, and stimulants Possible changes in reward sensitivity and reinforcement mechanisms Overlap between neural pathways involved in appetite regulation and substance use However, translating these findings to human populations has proven challenging

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[1] If side effects significantly impair your quality of life despite timing adjustments, your prescriber may consider dose modification or alternative treatment options