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This paper provides a review on the current evidence supporting the use of GLP-1 in experimental animal models and human trials with the ischemic and non-ischemic heart and discusses their molecular mechanisms and potential as a new therapeutic approach.

The results suggest that LVH, impaired mitophagy, and activation of NLRP3 inflammasome were present in TAC rats

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Diabetes and obesity expert Rajiv Kovil summed it up well - he says it probably moves the needle from a caloric restriction model to a metabolic engineering model