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Concurrent medications Medications that affect gastrointestinal motility, such as opioids, anticholinergics, certain antidepressants, and proton pump inhibitors, can interact with semaglutide to intensify side effects
Most significantly, patients who'd taken Wegovy for a year saw their need for loop diuretics decline by 17% on average, compared to an average 2.4% increase in diuretic use among those who got the placebo, the researchers said