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Diabetes Metab Syndr Clin Res Rev 11:225230 Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M (2015) Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury

[32] demonstrated that liraglutide compared to placebo did not improve amyloid deposition or cognition in participants with AD

52 In a phase 1b trial done to evaluate the safety, pharmacokinetics and pharmacodynamics of orforglipron in patients with T2DM, orforglipron resulted in significant reductions in HbA1c, fasting blood glucose and body weight, with an adverse event profile consistent with that of other GLP-1RA

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Supplementing your diet with additional prebiotic fiber sources dramatically increases the likelihood that the probiotic strains will colonize effectively and produce meaningful amounts of metabolites