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The largest decreases tend to require months

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Appetite hormones such as ghrelin rise, fullness hormones such as leptin fall, and metabolism slows slightly to conserve energy

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"While some plant compounds may indirectly influence GLP-1 pathways or mimic some GLP-1 effects, they are not equivalent to pharmaceutical GLP-1 receptor agonists," says Kumar

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Weight change: 2-4 pounds total loss from baseline (cumulative)

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