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(Related: Is long-term GLP-1 use safe
Staying hydrated helps

For type 2 diabetes, NICE guidance (NG28) recommends their use as second- or third-line therapy when metformin alone provides inadequate control, particularly in patients who would benefit from weight loss or where hypoglycaemia risk must be minimised

11, 2021, pp

Originally developed to treat Type 2 Diabetes, GLP-1s have proven to be highly effective, albeit very expensive, when prescribed for weight loss
