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Finally, the oxidation of polyunsaturated fatty acids (PUFA-PE) by LOX results in cellular ferroptosis [37] (Fig

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doi: 10.1146/annurev.me.34.020183.001251

This step is catalyzed by the vitamin B6 coenzyme pyridoxal phosphate, in reaction of homocysteine with serine to form cystathionine
