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In this study, we preliminarily revealed the role of DNA-PKcs in promoting the malignant phenotype of ATC and demonstrated the anti-ATC activity of its inhibitor, KU-57788

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the leucine-rich repeat kinase 2 (LRRK2) protein induces ferroptosis by acting on the System Xc/GSH/GPX4 pathway (51) and the m6A demethylase fat mass and obesity-associated protein can promote ferroptosis via the p53/SLC7A11 axis (39)