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Description
While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51

Chemosphere 289, 133147

Structure 7(1):8189

AMD is a heterogenic and multi-factorial disease that can also be influenced by numerous environmental and genetic risk factors [3,4,7], which significantly contribute to the development of the disease

10.1084/jem.2.5.543 106 SongX.ZhangH.ZhangY.GohB.BaoB.MelloS