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Revealing the drug resistance mechanisms and combination strategy will be essential to overcome resistance and improve treatment efficacy

Board PG, Pierce K
Previous work from our group demonstrated that intravenous administration of another primary RSNO, S -nitroso- N -acetylcysteine (SNAC), produces marked systemic vasodilation in normotensive and hypertensive Wistar rats 28 , consistent with findings reported by others 29,30
Riboflavin ameliorates cisplatin induced toxicities under photoillumination
Controlled studies are ongoing, but present data do favor microbiome modulation as an adjunct therapy