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At low concentrations, AM enhances membrane integrity and ion transport, whereas higher doses may exert inhibitory effects, possibly through hormetic oxidative modulation or direct membrane interactions

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However, strengths of the study include the community-based recruitment, the unmedicated and mostly medication-nave MDD group, and the relatively large control sample that matched MDD cases in terms of education and other sociodemographic variables [7]

The BBB is a highly specialized and tightly regulated semipermeable barrier that separates circulating blood from the brains extracellular fluid