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Mouritsen, Membrane-perturbing effect of fatty acids and lysolipids

Its protective function is mainly exerted through gene transcription regulation via all-trans retinoic acid, which activates antioxidant enzymes such as SOD, CAT, and GPx [52]

Dysbiosis of the human gut microbiome has been associated with various pathologies (Perry et al., 2016)

The body can synthesize glutathione from three amino acids glutamate, cysteine, and glycine but cysteine is the one that is most often in short supply

Furthermore, NRF2 accelerates cellular redox homeostasis by upregulating the transcriptional regulation of multiple NADPH-generating enzyme genes (e.g., G6PD) [26]