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Our results have demonstrated that PlexinB1 is expressed in the cytoplasm and around the nuclear envelope and that Sema4D is internalised by endocytosis, revealing a capacity to signal from endosomal receptors in the cell in a similar way to many other transmembrane receptor proteins such as Met [49]

In 2020, Boeing et al

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In further research, it was found that berberine achieved antioxidant effects by reducing the expression of pro-inflammatory factors, apoptotic factors and nuclear transcription factor B (NF-b), as well as up-regulating the expression of peroxlsome proliferator-activated receptor- coactlvator-1 (PGC-1) and manganese superoxide dismutase