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That is why a correlation between certain types of male infertility and the aberrant expression, localization, structure, and function of PI-PLC in human sperm has been determined

D.CarrollC

For example, the lactylation of K230 and K322 on ALDOA abolishes its interaction with dead-box deconjugate enzyme 17 (DDX17), thereby enhancing the regulatory function of DDX17

DAG-sensing PKC and PKD isoforms play a crucial role in the regulation of metabolic homeostasis and therefore might serve as targets for the treatment of metabolic disorders such as obesity and diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Frye R.E., Rossignol D.A