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J Clin Endocrinol Metab 109(2):e495e507

Tinsley, E., Bredin, P., Toomey, S., Hennessy, B

& Hunninghake, G

They may not be worth the cost, either

In conclusion, we identified a copper-dependent novel mechanism underlying kidney fibrosis in which upregulation of CTR1 leads to increased copper influx, which then increases LOX activity and thus promotes ECM crosslinking and fibrosis
