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This conservative approach has merit because it keeps a higher dose in reserve as a strategic tool

[30] At least one study has found that certain features of pathology are idiosyncratic to G93A and not extrapolatable to all ALS-causing mutations

A condition where the shoulder capsule thickens and tightens, causing progressive pain and severe range-of-motion loss

Treatment of patients with this condition who are experiencing prolonged paralysis following administration of succinylcholine involves close monitoring of patient status with maintained sedation and respiratory support using mechanical ventilation until the neuromuscular block is spontaneously resolved

They work through different mechanisms