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Long term administration of acetylcarnitine (1 month, in drinking water) increases the mitochondrial content in rat skeletal muscle [99], suggesting that acetylcarnitine stimulates mitochondrial proliferation, even if the latter is not detected after a short time of supplementation

High-resolution mass spectrometry (HRMS) offers strong resolution capabilities, enabling qualitative and quantitative analysis of unknown substances and significantly expanding the detection range of carnitines

Figure 3 3.5 Control analyses for age or TSH level as confounding factors In addition to the above planned statistical tests, we conducted two post hoc partial correlation analyses to examine possible confounding effects of age or TSH level as confounding factors

Animal models of drug self-administration, known for their strong validity in depicting drug intake and abuse, are considered standard models for elucidating human addiction behaviors 37

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