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When applied during peak activity periods (nocturnal phase), VNS suppresses pro-inflammatory gene expression (e.g., IL-6), reduces inflammatory responses, and enhances BBB integrity through upregulation of ZO-1 and occluding (152, 158)

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Mood and Cognitive Function Beyond weight management, MIC B12 injections may have positive effects on mood and cognitive function

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Skelton, L

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