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However, GSH concentrations were reduced in the liver [31,50]

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Foremost among those on immuno-suppressive therapies are those with auto-immune diseases

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Arguably, the substances involved in this context choline, betaine, vitamin B6, vitamin B12 (methylcobalamin), folate (methyl-THF) and SAM all have a much more direct connection to the symptoms attributed to homocysteine and are therefore often the root cause of a disease