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We traced its role as an upstream maker rather than a storefront, and that framing is the useful part
In the case of the developed IGF-1 MSIA-SRM, the use of the MSIA tips in comparison to beads translated into a 10-fold lower limit of detection and a 20-fold LLOQ for an extraction method requiring less than 30 minutes
Intriguingly, when using the same probes ex vivo in Ussing chambers, the difference is much less pronounced with a LMR of ~0.8 ex vivo vs
Shirose, M
Nat Neurosci 24:168175
