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Several studies, however, have described increased GSTP1 expression in drug-resistant cell lines following exposure to drugs which are not detoxified by glutathione conjugation (Wang et al, 1989), or which are not GSTP1 substrates (Tew, 1994)a direct role for GSTP1 in platinum chemosensitivity therefore remains to be unequivocally established

However, no significant correlation was detected between miR-769-5p and GGCT, leading to its exclusion from subsequent analyses (Fig

Most of what we know to date comes from a mix of preclinical research and the biological mechanisms each therapy targets

Environ Health Perspect, 49, 59-69

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