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Several cellular processes are involved in the pathogenesis of AIH, including liver metabolism, mitochondrial oxidative stress and dysfunction, sterile inflammation, endoplasmic reticulum stress, autophagy, and microcirculation dysfunction

Paweczyk et al
Similarly, advances in lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) research have revealed new avenues for treating autoimmune diseases [168]
Semaglutide may be especially familiar to patients because of its established role in obesity and diabetes care

doi: 10.1038/nbt.2508 60 JiangY.ZhengW.TranK.KamilarE.BariwalJ.MaH.et al
