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In vitro and preclinical work on hGH fragments (including modified forms related to AOD 9604) has also reported increased lipid oxidation and reduced lipogenesis in adipocyte and metabolic test systems, supporting its use as a tool compound to study fat mobilization and energy balance

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Notably, the co-culture of CMs and cardiac fibroblasts, which are two of the most critical cell types for studying cellular physiology, was explored for the first time in this research, according to the authors

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A quinolinium-based, selective NNMT inhibitor used to interrogate NNMT biology in cells and animal models of obesity, insulin resistance, and related metabolic phenotypes (commonly as the iodide salt