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Clinical evidence has established that elevated levels of the lipid peroxidation product 4-HNE in bronchoalveolar lavage fluid are significantly associated with poorer lung function in patients with neutrophilic asthma, underscoring its relevance as a biomarker for disease severity and potential treatment response (158)

[DOI] [PubMed] [Google Scholar] 292.Pillai A., Howell K.R., Ahmed A.O., Weinberg D., Allen K.M., Bruggemann J., Lenroot R., Liu D., Galletly C., Weickert C.S., et al

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Molecular mechanism of the inhibition and remodeling of human islet amyloid polypeptide (hIAPP 137 ) oligomer by resveratrol from molecular dynamics simulation