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The present-day research also focuses on using antioxidants for the chemoprevention of different types of cancer, including brain cancer, as antioxidants may reduce tumor growth and interfere with carcinogenesis [4]
Transcriptome studies in the heart and liver further confirmed that chronic stress induces broader reprogramming (2,503 and 2,236 DEGs, respectively) compared to acute stress (1,217 and 1,843 DEGs, respectively), with conserved upregulation of HSP genes ( HSP90AA1 , HSPA4 , HSPB8 ) and antioxidant genes ( GPX1 ), while tissue-specific adaptations involved immune signaling in the heart and metabolic remodeling in the liver [57]
