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H.YuY.CaoL

Therefore, we hypothesized that GCLC downregulation under high glucose conditions was a function of reduced HuR subcellular localization to the cytoplasm, as previously observed in cell culture models under these conditions ( 17, 26 )

4.2 Mechanisms of HIV/SIV-induced mtDNA damage and dysfunction HIV uses both direct and indirect mechanisms that compromise mtDNA integrity and mitochondrial function

It has been shown that the cytosolic APX imparts cross compartment protection of the other sub-cellular organellar APXs like mitochondrial APX, thylakoidal and stromal APXs hinting toward the fact that cytosolic AsA-GSH pathway plays an important role in protecting the other organelles during periods of stress (Davletova et al., Medicago sativa (Dalton et al., AsA-GSH pathway in peroxisome Peroxisomes are single membrane-bound subcellular organelles being involved in production as well as the degradation of H 2 O 2 and are sites for photorespiration, fatty acid -oxidation, glyoxylate cycle and ureide metabolism (Corpas et al., 2005)

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