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FP7-KBBE-2012-6, CP-TP-312184

In MDCK-MDR1 cells, efflux of GS-441524 was completely inhibited by pre-incubation with Valspodar (Table 3), suggesting GS-441524 is a substrate for the MDR1 transporter

AAI analysis also supported placement of DCMF in a novel genus based on a suggested ~70% AAI threshold [59], although DCMF and D
To test whether the special localization of ORF3a was important for its function in autophagy, different truncated ORF3a proteins were constructed and tested for their function in autophagy (Fig

Garvey WT, Frias JP, Jastreboff AM, le Roux CW, Sattar N, Aizenberg D, et al