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Furthermore, improper activation of protein kinase C and Rho can modulate the actin cytoskeleton and influence tight junction regulation and function [158]

Our own DiabetesMine correspondent Wil Dubois, who landed in the hospital with DKA, said this: The main symptoms of DKA that were told to watch for other than those associated with high blood sugar in the first place, like crazy thirst and peeing like a racehorse are nausea or vomiting, abdominal pain, fruity-smelling breath, rapid breathing, and confusion. Of course, you cant smell your own breath

Add to that the lack of a gold-standard test for deficiency, and you can see why its an easy issue to miss

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