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[] SeP interacts with LRP1 in the membrane of skeletal muscle, and subsequently, suppresses ROS-induced AMP-activated protein kinase (AMPK) phosphorylation and PGC-1 expression, thus, causes exercise resistance
Oxidative stress has long been associated with diabetic complications, but has only recently received attention as a possible reason for the development of diabetes (Houstis et al., 2014)

Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate

M.WasanE

Mol Metab 97:102158
