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Methodologically rigorous studies that couple pathway inhibition to predefined immune and clinical endpoints, deploy standardized biospecimen workflows and use harmonized safety reporting are required to determine whether neurotrophin-targeted strategies can remodel the osteosarcoma microenvironment toward durable immune control

[DOI] [PMC free article] [PubMed] [Google Scholar] Andreou A

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doi: 10.3390/molecules26092540, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 39.Shomali N, Onar O, Karaca B, Demirtas N, Cihan AC, Akata I, et al