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The accumulation of lipofuscin-like material may be the result of an imbalance between formation and disposal mechanisms

Conclusion This study firstly demonstrated the adverse effects of 8-week oral supplementation of exogenous l-carnitine on liver and kidney function in both female and male rats

Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR et al (2012) The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

Recommended directions for future research include developing biomarker-based diagnostic tools, optimizing combination therapies that target multiple pathophysiological pathways simultaneously, and integrating real-world data and digital health technologies for precise monitoring and management of ME/CFS

Benefits from the supplement combination were more pronounced in those who adhered to the low-calorie diet