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3B,C, the abscopal effect, as well as ferroptosis-related events in Tumor2 from TRL3-knockout mice receiving poly(I:C) plus RT treatment were vanished, indicating that TLR3 signaling activation is indispensable for poly(I:C) to promote abscopal effect of RT

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J Biol Chem (2000) 275:3823944

Equally important are in vitro and in vivo studies that will help us better understand how selenium affects the gut microbiome and its function