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The release of prostaglandins may be due to decreased stability of lysosomal membranes in the endometrial cells (79)

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The K303A mutant showed a 1,500-fold decrease in decarboxylation activity

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Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management

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