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Furthermore, various factors including aging, iatrogenesis, and the environmental factors can lead to basement membrane damage and therefore easier migration of melanocytes and melanin to skin layers and their accumulation within the dermal layer

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USA 104 814818 Altieri F, Grillo C, Maceroni M and Chichiarelli S 2008 DNA damage and repair: from molecular mechanisms to health implications

Science 263 , 969971 (1994)
