penile arterial endothelium has a lower glutathione level Oxidative Stress and New Pathogenetic Mechanisms in Endothelial Dysfunction: Potential Diagnostic Biomarkers and Therapeutic Targets Structural and functional abnormalities of

On the other hand, if you are self-administering, then the thigh is a more convenient location

Uptake and antioxidant effects of ergothioneine in human erythrocytes

It is proposed that repetitive micro-injuries to alveolar epithelial cells trigger abnormal epithelial-fibroblast communication, which eventually results in abnormal ECM accumulation and pathological lung remodeling (Heukels et al., 2019

Several mechanisms may explain GH resistance in HF: a) the systemic inflammation and elevated cytokines (e.g., TNF-, IL-6) downregulate GH receptors and post-receptor signaling in the liver and peripheral tissues

While this represents a higher per-treatment cost than oral supplements, the superior absorption and reduced frequency often make injections cost-competitive over time, particularly for those who dont absorb oral forms effectively