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BAP1 suppresses the expression of SLC7A11 to inhibit cystine uptake, leading to lipid peroxidation and ferroptosis

Onoue, S., Yamada, S

We refer readers to the FY 2022 IPPS/LTCH PPS final rule (Hospital IQR Program (86 FR 45376 through 45377), PCHQR Program (86 FR 45430 through 45431), and LTCH QRP (86 FR 45440 through 45441)) for more information on the initial review of the measure by the Measure Applications Partnership (MAP)

NDDSs offer several advantages, including an increased drug loading capacity, improved pharmacokinetic properties, passive or active targeting mechanisms for site-specific delivery, synergistic effects of multiple therapeutic agents, minimized drug resistance, and controlled release to enhance efficacy while reducing toxicity

Cai L, Koropatnick J, Cherian MG: Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro