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They should not be relied upon as a substitute for medical treatment or as the sole method of managing UFs

Although biochemically separated from the GSH system, the Trx system shares NADPH as a common reducing cofactor and serves as an alternative pathway for reducing disulfide bonds, making this system especially relevant if the GSH system has been compromised or rendered dysfunctional (Silva-Adaya et al., 2014)

Influences stressrelated pathways that affect neuroendocrine balance
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