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15 : eabg3449
A small prospective, randomized, open-label study involving men with obesity-related functional hypogonadism unresponsive to lifestyle modification examined the effects of liraglutide (3 mg daily) and testosterone replacement therapy (TRT)
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Deferoxamine (DFO), an FDA-approved iron chelator, effectively inhibits ferroptosis by binding free Fe 3 , decreasing ROS production, and upregulating ferroptosis-protective proteins such as GPX4, ferritin heavy chain 1 (FTH1), and system x [30]
Results : Mean (SD) age at baseline was 64.8 (2.8) years
