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Two more prospective studies involving women with PCOS indicated that melatonin administration of 23 mg/d for 26 months resulted in a reduction of androgens, LH, anti-Mllerian hormone, and BMI while increasing FSH levels [184, 185]

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In eukaryotes like Saccharomyces cerevisiae, lysine inhibits homocitrate synthase and activates protein kinase SCH9, which phosphorylates acetylglutamate kinase, creating a dual regulatory node

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