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Description
Symptoms appear in infants within four weeks of birth, and diagnosis is based on 5-oxoprolinuria, increased levels of 5-oxoproline in the urine

Freezing reconstituted peptides is generally not recommended

The 50100mg range appears in protocols because it approximates allometric scaling from effective rodent doses, but rigorous human pharmacokinetic data validating those numbers is sparse

Non-uniform refinement was performed with C-16 symmetry enforced, resulting in a reconstruction with a gold-standard FSC resolution of 4.04

It was discovered 130 years ago in baker's yeast (Saccharomyces cerevisiae)
