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[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Leas E.C., Hendrickson E.M., Nobles A.L., Todd R., Smith D.M., Dredze M., Ayers J.W

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In particular, during the acute phase, in which HCV replicates at a high rate, a marked oxidative stress due to the NOX4 isoform, ubiquitously expressed in parenchymal and non-parenchymal liver cells, has been observed, as well as a concomitant decrease in GSH