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In short, B12 keeps our brains sharp, energy levels up, and cells functioning correctly

Frost, J

Melatonin mitigates oxidative stress, inflammation processes, and cell apoptosis by upregulating the Nrf2 signaling pathway and downregulating COX-2 protein levels (135), as well as SOD, GPx, CAT, and Bcl-2 activities (136)

In addition, ML226 inhibition increased Lp glu on the PDHc-E2 (Supplementary Fig

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