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[PubMed: 20065996] 824

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Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors

Despite the absence of a prolonged anorectic effect, Cagrilintide produced a sustained and significant reduction in body weight in WT mice by 3.4 g after 21 days, while no such effect was observed in KO animals

Because they bypass the digestive system, injectable delivery ensures higher absorption rates compared to oral supplements