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The issue of drug resistance could be prevented by combining gefitinib, a therapeutic drug for patients with NSCLC with EGFR mutations, and BCH, a SLC7A5 inhibitor that reduces the phosphorylation level of mTOR and its downstream molecules (93)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Wang Z, Bergeron N, Levison BS, Li XS, Chiu S, Jia X, Koeth RA, Li L, Wu Y, Tang WHW, et al

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Safety of gemtuzumab ozogamicin as monotherapy or combination therapy in an expanded-access protocol for patients with relapsed or refractory acute myeloid leukemia

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