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While it remains to be seen whether this discovery in vitro can be translated to a therapeutic, i.e

Vitamin B12 is a water-soluble vitamin that plays a vital role in brain function and red blood cell production
Moreover, TJ protein loss and alteration, specifically decreased JAM-2 and zonula occludens-1 (ZO-1) levels, are characteristic of cocaine transit across the BBB (Srinivasan et al., 2015)

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10.1016/S0165-6147(98)01279-6 94 KiefferB
