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[PubMed: 28245459] 49

Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation

As a rule, a pore size of 300 to 700 is usually a good compromise in most situations encountered in affinity chromatography, since this gives fairly unrestricted diffusion for most biomolecules while also providing a relatively large surface area for retention [8]

Conclusion: SYNE1 genetic variants are associated with a spectrum of neurological disorders, particularly SYNE1 ataxia, which presents with both cerebellar and noncerebellar symptoms

Furthermore, we demonstrate that engineering for high affinity does not preclude pan-HLA cross-reactivity within and even beyond a given HLA supertype
