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Therefore, lactate and lactylation-related subtype transformation of astrocytes and microglia may play a crucial role in the onset and progression of neuroinflammation

Knobil, E

Specifically, our results show that the lifespan extension induced by mrps-5 RNAi was completely abolished in the C32E8.9 knockout strain, confirming that C32E8.9 is indeed necessary for this beneficial effect

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Relationships of clinical, physiologic, and inflammatory factors to extracellular BAL fluid and intracellular GSH and GSSG IL-13 upregulates 15LO1 pathway and lowers intracellular GSH IL-13 increases the expression and activity of 15LO1, while inducing binding to PEBP1 (6, 7, 10, 13)