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Five replicate titration curves were used to estimate sensitivity by spiking the positive control antibody (PC) into neat serum at 40 ng/mL and diluted 1:40

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These compounds selectively blocked t-LTD at L4-L2/3 synapses with no effect on t-LTP at the same synapses, which was instead blocked by the GluN2A subunit-preferring antagonist NVP-AAM077

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